Cell Validation | U373 (Human Glioma Cells) - BS-1101 Validation Data

Using the product: BS-1101Product Introduction:The serum is sourced from healthy fetal bovine serum collected aseptically; GMP purification workshop fully automatic filling production, with large batch size and small inter batch differences (using 4000L mixing tanks, maximum batc···

Cell validation | Hep3B 2.1-7 (human liver cancer cells) - BS-1105 validation data

1、 Using the product: BS-1105（1）Product IntroductionThe serum is sourced from sterile collection of high-quality fetal bovine serum aged 6-8 months; GMP purification workshop fully automatic filling production, with large batch size and small inter batch differences (using 400···

Procedure for Replacing Fetal Bovine Serum

Usually includes the following steps:1. Choose the appropriate serum Before replacing fetal bovine serum, it is necessary to select the appropriate serum based on cell type and experimental requirements. For example, some cells have adaptability to specific brands of serum, so wh···

Literature Selection | Inhibiting YAP1 activity can improve acute lung injury by promoting polarization of M2 macrophages

The polarization balance of M1/M2 macrophages plays an important role in regulating the inflammatory response during acute lung injury (ALI). YAP1 is a key protein in the Hippo-YAP1 signaling pathway, involved in macrophage polarization. The research conducted by Xu Wenyan's team···

Literature selection | Targeting membrane associated protein A1 in tumor associated macrophages as a therapeutic strategy for hepatocellular carcinoma

Hepatocellular carcinoma is a common malignant tumor with limited treatment options. At present, immunotherapy has limited efficacy in liver cancer cells. Membrane associated protein A1 is a protein associated with inflammation, immunity, and tumors. However, the role of membrane···

Literature selection | Tracking the cellular interactions between circRNA miRNAaxis and DNA cascade assembly supported by Cu metal organic framework

Circular RNA (circRNA) can serve as a molecular sponge for microRNA (miRNA), forming the circRNA miRNA axis and regulating the expression of downstream proteins. Although this mechanism has been widely reported in various biological processes, there is still a lack of reliable an···

Selected Literature | Yeast Nanoparticles Driven Photodynamic Immunotherapy for Tumors

Photodynamic therapy (PDT) uses a combination of light and photosensitizers to destroy cancer cells. However, due to various factors such as insufficient ROS generation and weak induction of immune responses, PDT alone is often insufficient to trigger effective anti-tumor respons···

Literature selection | Aline regulates PKM2 nuclear accumulation and histone H3 acetylation through the TAS1R1-mTOR-DDX39B signaling pathway, promoting milk synthesis

Valine is a branched chain amino acid that plays a crucial role in the process of milk synthesis. However, the exact effect of valine on cow lactation is still a research field. Therefore, the team led by Professor Cao Yu from Jilin University isolated bovine mammary epithelial c···

Selected Literature | Biological Stimulation of Lipoproteins by Furacil Gemcitabine for Prioritizing Targeting Glioblastoma and Overcoming Radiotherapy Resistance

Radiation therapy (RT) resistance is a major challenge in the treatment of glioblastoma multiforme (GBM), which is largely related to DNA repair, poor distribution of reactive free radicals in the tumor, and limited delivery of radiosensitizers to the tumor site. Inspired by the ···

Selected Literature | Peptide TK-HR in Traditional Chinese Medicine Frog Skin Accelerates Wound Healing by Activating Neuronal Activin-1 Receptors

Wound healing is a complex process and remains a significant challenge in clinical trials due to the lack of ideal therapeutic drugs. The team led by Professor Wu Jiena from Southern Medical University tested the ability of a new peptide TK-HR identified from frog skin to heal sk···