1. What is drug screening
Drug screening is a step in the modern drug development process that involves testing and obtaining compounds with specific physiological activity. It refers to the process of selecting compounds with high activity towards a specific target through standardized experimental methods from a large number of compounds or new compounds. It is a necessary process in the development of clinical new drugs.
Drug screening first requires a suitable screening model. The drug screening model is an experimental method used to demonstrate the pharmacological activity (biological activity, therapeutic effect) of a substance, which is one of the important conditions for finding and discovering drugs. In the long-term practice of searching for drugs, people have established a large number of various models for new drug screening, which have played a positive role in new drug discovery and research. The research on drug screening models has gone through three different stages of development: whole animal models, tissue and organ level screening models, and cell and molecular level drug screening models, each of which originated from the birth of a new technology.
2. The Application of Serum in Drug Screening
Serum also plays an important role in drug screening. By adding drugs to a culture medium containing serum, the effects of drugs on biological processes such as cell growth, proliferation, and differentiation can be observed, thereby evaluating the efficacy and safety of drugs. In addition, serum can also be used to construct drug tolerant cell models, providing strong support for drug development.
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