Selected Literature | Natural Isoflavones Photoglycyrrhizin Targeting PI3K γ as Adjuvant to Enhance the Sensitivity of MDA-MB-231 to Tamoxifen and DU145 to Paclitaxel

Guanggancao Ding is a natural isoflavone with estrogen receptor agonists and significant anti-tumor activity. In addition, Guanggancao Ding has a regulatory effect on the PI3K/AKT/mTOR pathway, but its exact target is still unclear. Lin Hongyan, a teacher from Changzhou Universit···

Selected literature | Mixed micelles loaded with hesperidin protect against acetaminophen induced acute liver injury by inhibiting the mtDNA cGAS STING pathway

Excessive acetaminophen (APAP) is the main cause of drug-induced acute liver failure, and its pathogenesis has not been elucidated, and there is a lack of effective preventive and therapeutic drugs. Hesperetin (Hes) is a rich flavanone found in citrus peel, which has good biologi···

Literature Selection | Accurate RNA Editing: Multi effect Immunotherapy of PD-L1 Resistant Colorectal Cancer Based on CRISPR/Cas13a Cascade Self Revealing Dual Precursor Nanocomponents

CRISPR/Cas13a is a powerful RNA editing system with enormous clinical potential for screening drug targets and targeting oncogenes or immune checkpoints that are currently untreatable or unavailable for drug use. The immunosuppressive tumor microenvironment and acquired drug resi···

Literature selection | Tracking the cellular interactions between circRNA miRNA axis and DNA cascade assembly supported by Cu metal organic framework

Circular RNA (circRNA) can serve as a molecular sponge for microRNA (miRNA), forming the circRNA miRNA axis and regulating the expression of downstream proteins. Although this mechanism has been widely reported in various biological processes, there is still a lack of reliable an···

Literature selection | Polyvinylpyrrolidone polysulfide nanoparticles protect against oxaliplatin induced intestinal toxicity in vitro and in vivo

Product Name: Fetal bovine serum Product Code: BS-1105 Cell Culture: NMC460 Figure 1. The cell culture used in this study is Opdesia fetal bovine serum (OXL), which is a first-line drug for the treatment of colon cancer with significant efficacy. Gut toxicity is a common side eff···

Selected literature | Extracellular vesicles from UTX knockout endothelial cells promote neural stem cell differentiation in spinal cord injury

Product Name: Fetal bovine serum Product Code: BS-1105 Cell Culture: Vascular endothelial cells, astrocytes Figure 1. The cell culture used in this study involves the crucial role of Opsey fetal bovine serum vascular endothelial cells in the pathological and physiological process···

Selected Literature | Study on the Optimal Immune Dose and Protective Effect of a Combination Vaccine of Mycobacterium bovis and Bovine Herpesvirus Type 1 Attenuated and Marker

Product Name: Fetal bovine serum Product Code: BS-1101 Cell Culture: MDBK Figure 1. The study used Opsey fetal bovine serum for cell culture. Bovine respiratory disease (BRD) is one of the most common diseases in the cattle industry; It is a globally prevalent multifactorial infe···

Selected Literature | Self Adjuvant Polyguanidine Nanovaccine for Cancer Immunotherapy

Product Name: Fetal bovine serum Product Code: BS-1101 Cell Culture: BMDC Figure 1. In this study, cells were cultured using Opsey fetal bovine serum, which utilizes the power of the innate immune system. Nanovaccines can induce tumor specific immune responses, which is a promisi···

Ding! Selected Literature | Acylated Ghrelin Promotes ThyPOK Acetylation, Activated PI3K/mTOR Signaling Pathway, and Promotes Milk Fat Synthesis in Bovine Breast Epithelial Cells

Product Name: Fetal bovine serum Product Code: BS-1105 Cell Culture: Milk cow mammary epithelial cells Figure 1. This study uses Omdesi fetal bovine serum Ghrelin to regulate various physiological activities in cell culture. However, the effect of this hormone on milk fat synthes···

Selected Literature | The Role and Mechanism of miR-871-3p/Megf8 in Regulating Formaldehyde Induced Cardiomyocyte Inflammation and Congenital Heart Disease

One The team led by Professor Yu Tao from Qingdao University studied the molecular mechanism of formaldehyde (FA) - induced congenital heart disease (CHD) through in vitro and in vivo models, and ultimately demonstrated the role of miR-871-3p in FA induced coronary heart disease ···